Product Name: Cleaved PARP (Asp214) (19F4) Mouse mAb (Human Specific)#9546
Application: Dilutions
Western Blotting: 1:2000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 13422-55-4
Product: Methylcobalamin
Specificity Sensitivity: Cleaved PARP (Asp214) (19F4) Mouse mAb (Human Specific) detects endogenous levels of the large fragment (89 kDa) of human PARP1 resulting from cleavage at aspartic acid 214. This antibody will detect high levels of full length PARP.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic PARP peptide corresponding to carboxy-terminal residues surrounding Asp214 in human PARP.
Background: PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress (1). This protein can be cleaved by many ICE-like caspases in vitro (2,3) and is one of the main cleavage targets of caspase-3 i
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27532210?dopt=Abstract
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