Product Name: Aprataxin (D5P3C) Rabbit mAb#52632
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 475085-57-5
Product: MRE-269
Specificity Sensitivity: Aprataxin (D5P3C) Rabbit mAb recognizes endogenous levels of total aprataxin protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Phe282 of human aprataxin protein.
Background: Aprataxin is a DNA repair protein that resolves DNA lesions (DNA adenylates) caused by abortive ligations in single-strand break repair, double-strand break repair and base excision repair (1). Aprataxin is recruited to sites of DNA damage by PARP1 (2). I
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18245654?dopt=Abstract
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