Product Name: β-Amyloid (1-40 Specific) (D8Q7I) Rabbit mAb#12990
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1384268-04-5
Product: SYP-5
Specificity Sensitivity: β-Amyloid (1-40 Specific) (D8Q7I) Rabbit mAb recognizes the Aβ-40 isoform of the β-amyloid peptides. This antibody does not cross-react with other β-amyloid peptides.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues at the carboxy terminus of human β-amyloid (1-40) peptide.
Background: Amyloid β (Aβ) precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms (1). The amino acid sequence of APP contains the amyloid domain, which can be released by a two-step proteolytic cleavage (1). The extracell
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19446582?dopt=Abstract
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