Product Name: Acetyl-p53 (Lys379) Antibody#2570
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 862189-95-5
Product: Mirodenafil
Specificity Sensitivity: Acetyl-p53 (Lys379) Antibody detects endogenous levels of p53 only when acetylated at Lys376 (mouse protein) or Lys382 (human protein).
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic acetylated peptide corresponding to residues surrounding Lys379 of mouse p53. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). p53 is phosphorylated at multiple sites in vivo a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27723831?dopt=Abstract
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