Product Name: ATF-6 (D4Z8V) Rabbit mAb#65880
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 66640-86-6
Product: Biotin Hydrazide
Specificity Sensitivity: ATF-6 (D4Z8V) Rabbit mAb recognizes endogenous levels of total ATF-6 protein.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ATF-6 protein.
Background: Activating Transcription Factor-6 (ATF-6) is a transmembrane glycoprotein of the endoplasmic reticulum (ER). Upon accumulation of improperly folded proteins in the ER, ATF-6 is cleaved liberating a 50 kDa amino-terminal fragment that translocates to the n
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23326416?dopt=Abstract
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