Product Name: APC6 (D8D8) Rabbit mAb#9499
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1133432-50-4
Product: GDC-0834 (S-enantiomer)
Specificity Sensitivity: APC6 (D8D8) Rabbit mAb recognizes endogenous levels of total APC6 protein. Based upon sequence alignment, this antibody is not predicted to cross-react with either APC8/CDC23 or APC3/CDC27.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human APC6 protein.
Background: Eukaryotic cell proliferation depends strictly upon the E3 ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C), whose main function is to trigger the transition of the cell cycle from metaphase to anaphase. The APC/C complex prom
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20616019?dopt=Abstract
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